Healthgevity NMN 1000+ 60 caps

Introducing a powerful, cutting-edge supplement designed to support and enhance healthy NAD+ levels—vital for energy, cellular repair, and overall vitality. This innovative formula combines NMN (Nicotinamide Mononucleotide), a precursor to NAD+, with TMG(Trimethylglycine), which helps optimize methylation and support detoxification. Added Pterostilbene, a potent antioxidant, helps protect cells from oxidative stress while promoting healthy aging, and Apigenin, a natural flavonoid, further supports cellular health and cognitive function. Together, these ingredients work synergistically to elevate NAD+ levels, boost energy support, improve metabolic function, and promote longevity.

Nicotinamide Mononucleotide (NMN): 1,000mg

Key Benefits:

• Boosts NAD+ Levels: NMN is a direct precursor to NAD+, an essential molecule for energy production and cellular repair. By replenishing NAD+, NMN combats age-related declines in mitochondrial function and supports optimal metabolism.
• Supports Longevity Pathways: NMN activates sirtuins, enzymes that regulate DNA repair, inflammation control, and cellular health.
• Enhances Physical and Cognitive Performance: Higher NAD+ levels improve endurance, recovery, and brain function.

Scientific Evidence:

• Studies show NMN supplementation restores NAD+ levels, improving mitochondrial function and lifespan in animal models【1】
• Human trials demonstrate NMN’s ability to enhance blood flow and muscle oxygenation【2】

Trimethylglycine (TMG) (as Betaine Anhydrous): 500mg

Key Benefits:

• Supports Methylation Processes: TMG acts as a methyl donor, critical for processing homocysteine into methionine. This helps maintain healthy DNA and supports NMN's conversion into NAD+.
• Protects Cells from Stress: TMG stabilizes proteins and cell membranes under osmotic stress, ensuring cellular integrity.
• Supports Heart and Liver Health: Helps support homocysteine levels and cardiovascular risk factors.

Scientific Evidence:

• Research highlights TMG’s role in enhancing cellular methylation and metabolic efficiency【3】【4】
• TMG improves physical endurance and energy production in athletes【5】

Pterostilbene: 50mg

Key Benefits:

• Antioxidant Powerhouse: A more bioavailable analog of resveratrol, pterostilbene neutralizes free radicals and protects against oxidative damage.
• Activates Sirtuins: Supports longevity by enhancing sirtuin activity, which depends on NAD+.
• Supports Cognitive Function: Protects brain cells from age-related decline, enhancing memory and focus.

Scientific Evidence:

• Studies suggest pterostilbene is more bioavailable and effective than resveratrol at promoting cellular health【6】【7】.
• Pterostilbene has anti-inflammatory effects, supporting cardiovascular and brain health【8】.

Apigenin: 50mg

Key Benefits:

• Inhibits CD38: Apigenin blocks CD38, an enzyme that depletes NAD+ levels, ensuring more NAD+ is available for critical cellular processes.
• Anti-Inflammatory Properties: Supports chronic inflammation, a key driver of aging and age-related diseases.
• Protects Against Oxidative Stress: Enhances cellular resilience by reducing oxidative damage to DNA, proteins, and lipids.

Scientific Evidence:

• Research confirms apigenin’s ability to inhibit CD38 and increase NAD+ availability【9】【10】.
• Apigenin also shows neuroprotective effects, supporting healthy brain aging【11

The Synergy of Science

By combining these four powerhouse ingredients, NMN 1000+ supports NAD+ production through multiple pathways:

• NMN: Directly replenishes NAD+ levels.
• TMG: Facilitates NMN metabolism via methylation.
• Pterostilbene: Protects and enhances NAD+ and Sirtuin activity.
• Apigenin: Reduces NAD+ depletion by inhibiting CD38.